| First Author | Oka T | Year | 1999 |
| Journal | Arch Biochem Biophys | Volume | 361 |
| Issue | 2 | Pages | 195-201 |
| PubMed ID | 9882446 | Mgi Jnum | J:52055 |
| Mgi Id | MGI:1327755 | Doi | 10.1006/abbi.1998.0968 |
| Citation | Oka T, et al. (1999) Identification and cloning of rat galectin-2: expression is predominantly in epithelial cells of the stomach. Arch Biochem Biophys 361(2):195-201 |
| abstractText | A complementary DNA clone preferentially expressed in the gastrointestinal tract was obtained from a rat stomach library. The protein coded by the clone had a single carbohydrate recognition domain having conserved motifs for beta-galactoside binding and showed 67% amino acid identity with human galectin-2. The recombinant protein synthesized in Escherichia coli could bind to an asialofetuin column and was eluted with beta-galactopyranoside. From these observations, we named the protein rat galectin-2 coded by the cDNA. The rat galectin-2 was predominantly expressed in the epithelial cells of stomach. Thus this protein may form a mucin layer cross-linking with the beta-galactoside moiety of glycoproteins. Copyright 1999 Academic Press. |
