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Comment :

Type  MGI:General Description  at E8.5, the neuroectoderm is expanded and folded laterally towards the surface ectoderm, leading to an apparent lateral shift of the cranial neuroectoderm/surface ectoderm junction at E8.5, the transition from the columnar epithelial morphology of the neuroectoderm to the cuboidal epithelium of the surface ectoderm is not as distinct and appears to be more gradual the ratio of cranial surface ectoderm to neuroectoderm is reduced by 2-fold in mutants