| Primary Identifier | MGI:2446110 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 209462 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable small GTPase binding activity and ubiquitin protein ligase activity. Predicted to be involved in several processes, including Golgi organization; protein K48-linked ubiquitination; and ubiquitin-dependent protein catabolic process. Predicted to be located in endoplasmic reticulum and nuclear body. Predicted to be active in Golgi membrane and nucleus. Is expressed in central nervous system; eye; foregut; skin; and testis. Orthologous to human HACE1 (HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1). PHENOTYPE: Mice homozygous for a null allele exhibit increased spontaneous and induced tumors. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
