Primary Identifier | IPR033108 | Type | Family |
Short Name | Jag1 |
description | Ligand binding triggers the proteolytic cleavage of NOTCH receptors, whichis mediated by distinct enzymes []. Jagged-1 (JAG2) is a ligand for the Notch receptors []. The Jagged-Notch signalling plays important roles in the maintenance of proliferating neural precursors [, ]and in kidney development []. |