Primary Identifier | MGI:1930079 | Organism | mouse, laboratory |
Chromosome | 19 | NCBI Gene Number | 56473 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables stearoyl-CoA 9-desaturase activity. Predicted to be involved in arachidonic acid metabolite production involved in inflammatory response; lipid metabolic process; and positive regulation of cellular response to oxidative stress. Predicted to act upstream of or within fatty acid biosynthetic process. Predicted to be located in membrane. Is expressed in several structures, including adrenal gland; genitourinary system; nervous system; and retina. Orthologous to human FADS2 (fatty acid desaturase 2). PHENOTYPE: Mice homozygous for a null allele display absence of long-chain polyunsaturated fatty acids, infertility, arrest of spermiogenesis and folliculogenesis, and impaired platelet function. [provided by MGI curators] |