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Protein Coding Gene : Fads2 fatty acid desaturase 2

Primary Identifier  MGI:1930079 Organism  mouse, laboratory
Chromosome  19 NCBI Gene Number  56473
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables stearoyl-CoA 9-desaturase activity. Predicted to be involved in arachidonic acid metabolite production involved in inflammatory response; lipid metabolic process; and positive regulation of cellular response to oxidative stress. Predicted to act upstream of or within fatty acid biosynthetic process. Predicted to be located in membrane. Is expressed in several structures, including adrenal gland; genitourinary system; nervous system; and retina. Orthologous to human FADS2 (fatty acid desaturase 2).
PHENOTYPE: Mice homozygous for a null allele display absence of long-chain polyunsaturated fatty acids, infertility, arrest of spermiogenesis and folliculogenesis, and impaired platelet function. [provided by MGI curators]
  • synonyms:
  • MGI:1920207,
  • fatty acid desaturase 2,
  • RIKEN cDNA 2900042M13 gene,
  • Fads2,
  • Fadsd2,
  • Fads2a,
  • 2900042M13Rik

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

1 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

6 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For