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Allele : Col1a1<tm2(tetO-LIN28B)Gqda> collagen, type I, alpha 1; targeted mutation 2, George Q Daley
Primary Identifier  MGI:5294612 Allele Type  Targeted
Attribute String  Humanized sequence, Inducible, Inserted expressed sequence, RMCE-ready Gene  Col1a1
Transmission  Germline Strain of Origin  (C57BL/6 x 129S4/SvJae)F1
Induced With  doxycycline/tetracycline Is Recombinase  false
Is Wild Type  false
description  The allele was made in KH2 cells that carry Gt(ROSA)26Sortm1(rtTA*M2)Jae and Col1a1tm13(neo/hygro*)Jae (J:159351). This allele was generated with Col1a1tm13(neo/hygro*)Jae.
molecularNote  RMCE on KH2 cells inserted a construct, which contains (5' to 3') a splice acceptor, 2 polyadenylation sequence, tetracycline operator, a flag-tagged human LIN28B cDNA, and an SV40 polyadenylation signal, into the 3'UTR. No expression of the inserted gene is detected in the absence of doxycycline treatment.
  • mutations:
  • Insertion
  • synonyms:
  • iLIN28B,
  • iLIN28B
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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0 Driven By

22 Publication categories

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