First Author | Liddle J | Year | 2009 |
Journal | Bioorg Med Chem Lett | Volume | 19 |
Issue | 9 | Pages | 2504-8 |
PubMed ID | 19349179 | Mgi Jnum | J:148789 |
Mgi Id | MGI:3846490 | Doi | 10.1016/j.bmcl.2009.03.034 |
Citation | Liddle J, et al. (2009) 4-Phenyl-7-azaindoles as potent and selective IKK2 inhibitors. Bioorg Med Chem Lett 19(9):2504-8 |
abstractText | The synthesis and SAR of a novel series of IKK2 inhibitors are described. Modification around the hinge binding region of the 7-azaindole led to a series of potent and selective inhibitors with good cellular activity. |