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Publication : 4-Phenyl-7-azaindoles as potent and selective IKK2 inhibitors.

First Author  Liddle J Year  2009
Journal  Bioorg Med Chem Lett Volume  19
Issue  9 Pages  2504-8
PubMed ID  19349179 Mgi Jnum  J:148789
Mgi Id  MGI:3846490 Doi  10.1016/j.bmcl.2009.03.034
Citation  Liddle J, et al. (2009) 4-Phenyl-7-azaindoles as potent and selective IKK2 inhibitors. Bioorg Med Chem Lett 19(9):2504-8
abstractText  The synthesis and SAR of a novel series of IKK2 inhibitors are described. Modification around the hinge binding region of the 7-azaindole led to a series of potent and selective inhibitors with good cellular activity.
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