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Protein Coding Gene : Dlgap4 DLG associated protein 4
Primary Identifier  MGI:2138865 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  228836
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable molecular adaptor activity and protein domain specific binding activity. Involved in modification of postsynaptic structure and regulation of synapse maturation. Located in synapse. Is active in several cellular components, including cholinergic synapse; glutamatergic synapse; and neuromuscular junction. Is expressed in nervous system and neural retina. Used to study autism spectrum disorder. Orthologous to human DLGAP4 (DLG associated protein 4).
PHENOTYPE: Mice homozygous for a null allele display impaired dendrite morphology, increased mean postsynaptic density area, and impaired vocal communication and social interaction. [provided by MGI curators]
  • synonyms:
  • MGI:2385162,
  • PSD-95/SAP90 binding protein 4,
  • DLG associated protein 4,
  • DAP4,
  • cDNA sequence BC024558,
  • SAP90/PSD-95-associated protein 4,
  • MGC:37636,
  • WBP16,
  • expressed sequence AI225853,
  • AI225853,
  • BC024558,
  • Dlgap4,
  • Sapap4,
  • mKIAA0964
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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

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Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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3 Pathways

Trail: ProteinCodingGene

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Expression

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Phenotype

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Disease

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