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Allele : Rr127<tm3.1Ebres> regulatory region 127; targeted mutation 3.1, Emery H Bresnick
Primary Identifier  MGI:6194744 Allele Type  Targeted
Attribute String  Modified regulatory region Gene  Rr127
Transmission  Germline Strain of Origin  129S1/Sv-Oca2<+> Tyr<+> Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A 257 bp region (chr6:88116954–88117210 on build GRCm38/mm10) upstream of the Gata2 gene was replaced with a loxP site flanked neomycin resistance gene cassette. The neo cassette was subsequently removed through cre-mediated recombination. This region, located approximately 77 kb upstream of the ATG translation start site, is an enhancer containing two GATA motifs (WGATAR) and one E-box (CANNTG).
  • mutations:
  • Insertion,
  • Intergenic deletion
  • synonyms:
  • -77<->,
  • -77<->,
  • Gata2<tm3.1Ebres>,
  • Gata2<tm3.1Ebres>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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