| First Author | Ichiki T | Year | 1994 |
| Journal | Biochim Biophys Acta | Volume | 1189 |
| Issue | 2 | Pages | 247-50 |
| PubMed ID | 8292631 | Mgi Jnum | J:16503 |
| Mgi Id | MGI:64578 | Doi | 10.1016/0005-2736(94)90072-8 |
| Citation | Ichiki T, et al. (1994) Cloning of the cDNA and the genomic DNA of the mouse angiotensin II type 2 receptor. Biochim Biophys Acta 1189(2):247-50 |
| abstractText | Of the two major isoforms of the angiotensin II receptors, type 1 (AT1) and type 2 (AT2), little is known about the structure and features of AT2. We cloned a mouse AT2 cDNA from a mouse fetus cDNA library and an AT2 genomic DNA from a 129SV mouse genomic DNA library. The amino acid sequence of the mouse AT2 (363 residues) deduced from a mouse cDNA clone showed seven membrane-spanning domains. Amino acid identity of the mouse AT2 with mouse AT1 is 37%, and 98% with rat AT2. The genomic DNA (4.4 kb) contained three exons and two introns and the entire coding region was contained in the third exon. |
