Primary Identifier | MGI:5428935 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Aim2 |
Transmission | Germline | Strain of Origin | C57BL/6NTac |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A loxP site was inserted upstream of exon 5 and a neo cassette and loxP site were inserted downstream of exon 5. Cre mediated recombination deleted exon 5 and the neo cassette. Western blot analysis confirmed the absence of gene expression in bone marrow derived macrophages from homozygous mice. |