Primary Identifier | IPR044087 | Type | Family |
Short Name | NahD-like |
description | NahD is a 2-hydroxychromene-2-carboxylate isomerase (also known as HCCA isomerase) converts HCCA, a hemiketal formed spontaneously after ring cleavage of 1,2-dihydroxynaphthalene by a dioxygenase, into cis-o-hydroxybenzylidenepyruvate (cHBPA). This is the fourth reaction in a six-step pathway that converts naphthalene into salicylate [, ]. HCCA isomerase is unique to bacteria that degrade polycyclic aromatic compounds. It is closely related to the eukaryotic protein, GSH transferase kappa (GSTK) []. |