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Protein Coding Gene : Parn poly(A)-specific ribonuclease (deadenylation nuclease)

Primary Identifier  MGI:1921358 Organism  mouse, laboratory
Chromosome  16 NCBI Gene Number  74108
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable several functions, including cation binding activity; poly(A)-specific ribonuclease activity; and protein kinase binding activity. Acts upstream of or within nuclear-transcribed mRNA poly(A) tail shortening. Predicted to be located in nuclear speck and nucleolus. Predicted to be active in glutamatergic synapse; nucleus; and postsynapse. Is expressed in 2-cell stage embryo; central nervous system; and genitourinary system. Human ortholog(s) of this gene implicated in autosomal recessive dyskeratosis congenita 6. Orthologous to human PARN (poly(A)-specific ribonuclease).
PHENOTYPE: Mice homozygous for a null allele die prior to E11.5. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA 1200003I18 gene,
  • poly(A)-specific ribonuclease (deadenylation nuclease),
  • DAN,
  • Parn,
  • 1200003I18Rik

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Genome

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0 Exons

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0 Involved In Mutations

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0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

5 Pathways

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Expression

Gene --> Expression annotations

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Disease

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