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Protein Domain : Exocrine gland-secreted peptide Esp1/Esp22

Primary Identifier  IPR032253 Type  Family
Short Name  Esp1/Esp22
description  Exocrine gland-secreting peptide Esp1 is produced by the rodent male extraorbital lacrimal gland to be secreted into the tear fluid. Other mice including females detect these peptides through receptors in the vomeronasal organ, and the receptors report information on mouse-strain, sex and species [, , ]. Esp22 is produced by juveniles and functions as a mating inhibitor []. The peptides are short, all carrying an N-terminal signal peptide to indicate they are for secretion which accounts for much of the common conservation.

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42 Protein Domain Regions