| Primary Identifier | IPR028666 | Type | Family |
| Short Name | SNX17 |
| description | Sorting nexin-17 (SNX17) belongs to the sorting nexin family, which contains a conserved PX (phox homology) domain that may be responsible for binding to specific phosphoinositides []. SNX17 also possess an additional FERM-like domain [].SNX17 is a critical regulator of endosomal recycling of numerous receptors, channels, and other transmembrane proteins. It binds to Asn-Pro-Xaa-Tyr (NPxY) sequences in the cytoplasmic tails of cargo such as LDL receptors and the amyloid precursor protein []. |
