Primary Identifier | MGI:1927868 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 56273 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable several functions, including identical protein binding activity; transcription corepressor activity; and tubulin binding activity. Predicted to be involved in several processes, including cellular response to reactive oxygen species; peroxisome transport along microtubule; and protein import into peroxisome matrix. Predicted to act upstream of or within protein transport. Located in peroxisomal membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in peroxisome biogenesis disorder 13A. Orthologous to human PEX14 (peroxisomal biogenesis factor 14). PHENOTYPE: Homozygous disruption of this locus results in embryonic lethality. [provided by MGI curators] |