| First Author | Schiebel E | Year | 1995 |
| Journal | Trends Cell Biol | Volume | 5 |
| Issue | 5 | Pages | 197-201 |
| PubMed ID | 14731449 | Mgi Jnum | J:24909 |
| Mgi Id | MGI:72625 | Doi | 10.1016/s0962-8924(00)88999-0 |
| Citation | Schiebel E, et al. (1995) In search of a function for centrins. Trends Cell Biol 5(5):197-201 |
| abstractText | Spindle pole bodies, basal bodies and centrosomes are morphologically quite different structures that nevertheless perform similar microtubule-organizing functions in diverse cell types. The recent discoveries that both centrins and gamma-tubulin are common components of these structures suggest a molecular basis for their common functions. The role of centrins is just beginning to be investigated. These filament-associated proteins bind Ca2+. The filaments contract at least in certain circumstances by an ATP-independent mechanism. However, yeast centrin is clearly involved in the duplication of the spindle pole body. A common molecular mechanism may underlie these two apparently different functions. |
