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Allele : Tcf4<tm1Zhu> transcription factor 4; targeted mutation 1, Yuan Zhuang
Primary Identifier  MGI:2387399 Allele Type  Targeted
Attribute String  Null/knockout Gene  Tcf4
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
description  ES cell line = EFC-1.
molecularNote  The insertion of a neomycin selection cassette deleted sequence encoding the carboxy terminal, including a portion of the basic helix-loop-helix (bHLH) domain. The disruption of the bHLH precludes dimerization, thereby preventing the potential for DNA binding activity.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • E2-2<->,
  • Tcf4<->,
  • Tcf4<->,
  • E2-2<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

17 Publication categories

Trail: Allele




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