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Protein Domain : Negative elongation factor E

Primary Identifier  IPR033102 Type  Family
Short Name  NELFE
description  Negative elongation factor E (NELFE) is an essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II []. The NELF complex is found in higher eukaryotes, but is absent in some species of nematodes, S. cerevisiae, and plants. It may repress transcription by inducing transcriptional pausing []and can be regulated by integrator complex subunits (INTScom) [].

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5 Protein Domain Regions