Primary Identifier | MGI:3710108 | Allele Type | Gene trapped |
Attribute String | Null/knockout, Reporter | Gene | Fkbp5 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The pGT1Lxf gene trap vector that contains a splice acceptor and beta-geo was inserted into intron 4. Northern blot, quantitative RT-PCR and Western blot confirmed the expression of a fusion transcript and protein that lacked the peptidyl-prolyl cis/trans-isomerase-like domain and all three TPR domains critical for the protein's function. |