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Protein Coding Gene : Mov10 Mov10 RISC complex RNA helicase
Primary Identifier  MGI:97054 Organism  mouse, laboratory
Chromosome  3 NCBI Gene Number  17454
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable 5'-3' RNA helicase activity and RNA binding activity. Involved in regulation of neuron projection arborization and retrotransposon silencing. Located in cytosol and nucleus. Is expressed in brain; gut; sensory organ; testis; and turbinate bone primordium. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human MOV10 (Mov10 RNA helicase).
PHENOTYPE: Homozygous knockout is embryonic lethal. Heterozygous knockout leads to reduced dendritic branching of neurons, which affects anxiety- and/or activity-related behavior. [provided by MGI curators]
  • synonyms:
  • Moloney leukemia virus 10,
  • MGD-MRK-12359,
  • Mov10,
  • C77703,
  • Mov10 RISC complex RNA helicase,
  • Mov-10,
  • expressed sequence C77703,
  • MGI:2140051,
  • MGD-MRK-12377
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Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

Trail: ProteinCodingGene

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

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0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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