|  Help  |  About  |  Contact Us

Protein Coding Gene : Tnks tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase

Primary Identifier  MGI:1341087 Organism  mouse, laboratory
Chromosome  8 NCBI Gene Number  21951
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable histone binding activity; pentosyltransferase activity; and zinc ion binding activity. Predicted to be involved in several processes, including positive regulation of canonical Wnt signaling pathway; post-translational protein modification; and regulation of chromosome organization. Predicted to act upstream of or within several processes, including Wnt signaling pathway; mRNA transport; and protein transport. Located in cytosol. Is expressed in several structures, including blastocyst; central nervous system; early embryo; neural retina; and oocyte. Orthologous to human TNKS (tankyrase).
PHENOTYPE: Mice homozygous for a null allele fail to exhibit any abonormalities. Male mice homozygous for a gene trapped allele exhibit decreased fat pad weight, increased metabolism, hyperinsulinemia, and hypoglycemia. [provided by MGI curators]
  • synonyms:
  • C86528,
  • D130072O21Rik,
  • Tnks,
  • Parp5a,
  • expressed sequence AI662855,
  • RIKEN cDNA 4930554K12 gene,
  • tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase,
  • 4930554K12Rik,
  • tankyrase 1,
  • mTNKS1,
  • TANK1,
  • MGI:2142612,
  • expressed sequence C86528,
  • AI662855,
  • MGI:2142876,
  • MGI:1922501,
  • RIKEN cDNA D130072O21 gene

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

12 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For