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Protein Coding Gene : Pvr poliovirus receptor
Primary Identifier  MGI:107741 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  52118
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables dynein light chain binding activity. Acts upstream of or within cell migration and cell-cell adhesion. Located in cell surface and plasma membrane. Orthologous to human PVR (PVR cell adhesion molecule).
PHENOTYPE: Mice homozygous for one null allele have a reduced antibody response to oral immunization. Mice homozygous for a different null allele exhibit reduced susceptibility to chemically induced colon cancer. [provided by MGI curators]
  • synonyms:
  • necl-5,
  • RIKEN cDNA 3830421F03 gene,
  • mE4,
  • Tage4,
  • MGI:1196266,
  • Pvr,
  • D7Ertd458e,
  • DNA segment, Chr 7, ERATO Doi 458, expressed,
  • MGI:1917954,
  • MGD-MRK-36317,
  • 3830421F03Rik,
  • tumor-associated antigen 1,
  • CD155,
  • Taa1,
  • poliovirus receptor
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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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8 Pathways

Trail: ProteinCodingGene

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Gene --> Protein-Protein Interactions

Expression

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Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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