Primary Identifier | MGI:5905291 | Allele Type | Chemically induced (ENU) |
Attribute String | Null/knockout | Gene | Taco1 |
Strain of Origin | C57BL/6NCrlAnu | Is Recombinase | false |
Is Wild Type | false | Project Collection | APF ENU Mutagenesis |
molecularNote | ENU treatment caused a T491A substitution in exon 3, which changes isoleucine codon 164 into an asparagine codon (p.Ile164Asn). Ile164 is a conserved residue and in homozygous mice virtually no protein is detected in liver and heart mitochondria via immunoblotting. |