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Publication : A new locus (Mtv-4) for endogenous mammary tumor virus expression and early mammary tumor development in the SHN mouse strain.

First Author  Imai S Year  1983
Journal  J Natl Cancer Inst Volume  71
Issue  3 Pages  517-21
PubMed ID  6310199 Mgi Jnum  J:7178
Mgi Id  MGI:55649 Citation  Imai S, et al. (1983) A new locus (Mtv-4) for endogenous mammary tumor virus expression and early mammary tumor development in the SHN mouse strain. J Natl Cancer Inst 71(3):517-21
abstractText  The SHN mouse strain, which has a high incidence of mammary cancer, developed by inbreeding and selection from Swiss stock mice by Dr. H. Nagasawa and co-workers (Meiji University, Tokyo, Japan), harbored an endogenous mammary tumor virus (MTV) responsible for a high frequency of mammary tumors early in life. The locus was called Mtv-4 and was only comparable with Mtv-2 of the GR mouse strain in its inducing capacity of mammary cancer. Molecular hybridization with 32P-labeled MTV complementary DNA showed that the characteristic Mtv-2 bands of the GR strain were absent in the SHN strain.
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