| First Author | Hilliker C | Year | 1992 |
| Journal | Genomics | Volume | 13 |
| Issue | 2 | Pages | 472-4 |
| PubMed ID | 1377168 | Mgi Jnum | J:920 |
| Mgi Id | MGI:49452 | Doi | 10.1016/0888-7543(92)90276-x |
| Citation | Hilliker C, et al. (1992) Assignment of the gene coding for the alpha 2-macroglobulin receptor to mouse chromosome 15 and to human chromosome 12q13-q14 by isotopic and nonisotopic in situ hybridization. Genomics 13(2):472-4 |
| abstractText | The assignment of the gene encoding the alpha 2-macroglobulin receptor (A2MR), which was first described as the low-density lipoprotein receptor-related protein, was confirmed by nonisotopic and isotopic in situ hybridizations on normal human metaphases to the region 12q13-q14. The same human cDNA, which has 95% sequence identity with the mouse A2mr, was hybridized to metaphases containing the Robertsonian translocation Rb(6;15)1Ald. The mouse A2mr gene was assigned to chromosome 15 in the region B2-D1. This locus and other loci on mouse chromosome 15 have been shown to be homologous with loci on human chromosome 12q. |
