| First Author | Klein J | Year | 1990 |
| Journal | Trends Genet | Volume | 6 |
| Issue | 1 | Pages | 7-11 |
| PubMed ID | 2183415 | Mgi Jnum | J:23658 |
| Mgi Id | MGI:71533 | Doi | 10.1016/0168-9525(90)90042-5 |
| Citation | Klein J, et al. (1990) The major histocompatibility complex and human evolution. Trends Genet 6(1):7-11 |
| abstractText | Many alleles at the human major histocompatibility complex (HLA) loci diverged before the divergence of humans and great apes from a common ancestor. This fact puts a lower limit on the size of the bottleneck in human evolution: the genus Homo must have been founded by no less than ten and probably by more than 10,000 individuals. |
