Primary Identifier | MGI:2663016 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Parp2 |
Transmission | Germline | Strain of Origin | 129S2/SvPas |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The gene was disrupted by insertion of a PGK-hygromycin cassette into exon 9 (at isoleucine 285) via homologous recombination. Absence of gene expression in homozygous mutant animals was confirmed by Western blot analysis of testis proteins using polyclonal antibodies against the catalytic domain or N-terminal domain. |