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Allele : Parp2<tm1Jmdm> poly (ADP-ribose) polymerase family, member 2; targeted mutation 1, Josiane Menissier de Murcia

Primary Identifier  MGI:2663016 Allele Type  Targeted
Attribute String  Null/knockout Gene  Parp2
Transmission  Germline Strain of Origin  129S2/SvPas
Is Recombinase  false Is Wild Type  false
molecularNote  The gene was disrupted by insertion of a PGK-hygromycin cassette into exon 9 (at isoleucine 285) via homologous recombination. Absence of gene expression in homozygous mutant animals was confirmed by Western blot analysis of testis proteins using polyclonal antibodies against the catalytic domain or N-terminal domain.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • parp-2<->,
  • parp-2<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

25 Publication categories

Trail: Allele