Primary Identifier | MGI:2384312 | Organism | mouse, laboratory |
Chromosome | X | NCBI Gene Number | 236733 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable cysteine-type deubiquitinase activity; cysteine-type endopeptidase activity; and transcription corepressor binding activity. Predicted to act upstream of or within proteolysis. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus. Is expressed in brain; dorsal root ganglion; and spinal cord. Orthologous to human USP11 (ubiquitin specific peptidase 11). PHENOTYPE: Male mice hemizygous for a null allele display enlarged prostate glands and hyperplastic prostate gland epithelium. Female homozygous null mice are viable. [provided by MGI curators] |