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Protein Coding Gene : Zfp516 zinc finger protein 516

Primary Identifier  MGI:2443957 Organism  mouse, laboratory
Chromosome  18 NCBI Gene Number  329003
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables DNA-binding transcription factor binding activity and cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including adipose tissue development; brown fat cell differentiation; and positive regulation of cold-induced thermogenesis. Located in nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human ZNF516 (zinc finger protein 516).
PHENOTYPE: Mice homozygous for a null allele die immediately after birth and show decreased white adipose tissue cell size, and abnormal presumptive brown adipose tissue morphology with abnormal mitochondria at E20.5. [provided by MGI curators]
  • synonyms:
  • C330029B10Rik,
  • zinc finger protein 26-like,
  • MGI:1926951,
  • RIKEN cDNA C330029B10 gene,
  • Zfp26l,
  • mKIAA0222,
  • zinc finger protein 516,
  • Zfp516

Features --> Cross References

Genome

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For