| First Author | Marcinkiewicz M | Year | 1994 |
| Journal | Neurosci Lett | Volume | 177 |
| Issue | 1-2 | Pages | 91-4 |
| PubMed ID | 7824189 | Mgi Jnum | J:20608 |
| Mgi Id | MGI:68688 | Doi | 10.1016/0304-3940(94)90052-3 |
| Citation | Marcinkiewicz M, et al. (1994) Pan-neuronal mRNA expression of the secretory polypeptide 7B2. Neurosci Lett 177(1-2):91-4 |
| abstractText | The polypeptide 7B2 exhibits a widespread distribution in the CNS and in the endocrine tissues. By in situ hybridization in the mouse tissues, we detected 7B2-mRNA transcripts in most, if not all, neurons of the brain and spinal cord, and in the cranial and spinal ganglia. 7B2-mRNA was undetectable in supportive glial cells, ependymal cells and endothelial cells. In embryonic tissues, 7B2-mRNA expression was observed at midgestation, starting on day 11. Both differentiated neurons and neuronal precursors have been shown to express 7B2 transcript. We conclude that 7B2-mRNA is a good molecular marker of developing and definitive neurons. |
