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Protein Coding Gene : Mrln myoregulin

Primary Identifier  MGI:1916813 Organism  mouse, laboratory
Chromosome  10 NCBI Gene Number  69563
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Enables enzyme inhibitor activity. Acts upstream of or within negative regulation of calcium ion import into sarcoplasmic reticulum and response to wounding. Located in sarcoplasmic reticulum membrane. Is expressed in several structures, including diaphragm; heart; leg muscle; somite; and tongue. Orthologous to human MRLN (myoregulin).
PHENOTYPE: Mice homozygous for a knock-out allele show improved exercise performance and enhanced Ca2+ handling in skeletal muscle. Mice homozygous for another knock-out exhibit reduced myofiber numbers and muscle regeneration. [provided by MGI curators]
  • synonyms:
  • Linc-RAM,
  • 2310015B20Rik,
  • MLN,
  • myoregulin,
  • Mrln,
  • RIKEN cDNA 2310015B20 gene

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For