Primary Identifier | MGI:2679913 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Cdk2 |
Transmission | Germline | Strain of Origin | 129S1/Sv-Oca2<+> Tyr<+> Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exon 4 was replaced with a neomycin resistance gene flanked by FRT sites. In spite of truncated transcript consisting of exons 1 through 3 detected by RT-PCR analysis, neither protein nor kinase activity was detected in samples obtained from homozygous mutant mice. |