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Allele : Cdk2<tm1Kald> cyclin dependent kinase 2; targeted mutation 1, Philipp Kaldis

Primary Identifier  MGI:2679913 Allele Type  Targeted
Attribute String  Null/knockout Gene  Cdk2
Transmission  Germline Strain of Origin  129S1/Sv-Oca2<+> Tyr<+> Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 4 was replaced with a neomycin resistance gene flanked by FRT sites. In spite of truncated transcript consisting of exons 1 through 3 detected by RT-PCR analysis, neither protein nor kinase activity was detected in samples obtained from homozygous mutant mice.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Cdk2<->,
  • Cdk2<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

23 Publication categories