|  Help  |  About  |  Contact Us

Protein Coding Gene : Akap4 A kinase anchor protein 4

Primary Identifier  MGI:102794 Organism  mouse, laboratory
Chromosome  X NCBI Gene Number  11643
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables protein kinase A binding activity. Involved in flagellated sperm motility. Acts upstream of or within several processes, including cell surface receptor protein serine/threonine kinase signaling pathway; establishment of protein localization; and sperm flagellum assembly. Located in Z disc; perinuclear region of cytoplasm; and sperm flagellum. Orthologous to human AKAP4 (A-kinase anchoring protein 4).
PHENOTYPE: Inactivation of this locus results in male infertility due to impaired sperm motility. Heterozygous mutant females show no reproductive defects. [provided by MGI curators]
  • synonyms:
  • Akap4,
  • MGD-MRK-19702,
  • fibrous sheath component 1,
  • Fsc1,
  • A kinase anchor protein 4

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For