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Allele : Rb1<tm1.1Ezac> RB transcriptional corepressor 1; targeted mutation 1.1, Eldad Zacksenhaus
Primary Identifier  MGI:6887862 Allele Type  Targeted
Gene  Rb1 Transmission  Germline
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  Serine to alanine substitutions at amino acids 800 and 804 (S800A, S804A) and threonine to alanine substitutions at amino acids 814 and 819 (T814A, T819A) were introduced in exon 23 and a loxP flanked PGK-neo was inserted downstream of exon 23. These substitutions abolish phosphorylation at these sites. Cre-mediated recombination removed the neomycin cassette.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Rb<K4>,
  • Rb<deltaK4>,
  • Rb<K4>,
  • Rb<deltaK4>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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