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Protein Coding Gene : Ap2b1 adaptor-related protein complex 2, beta 1 subunit
Primary Identifier  MGI:1919020 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  71770
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable clathrin binding activity. Involved in clathrin-dependent endocytosis and postsynaptic neurotransmitter receptor internalization. Acts upstream of or within circulatory system development and kidney development. Part of AP-2 adaptor complex. Is active in glutamatergic synapse. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human AP2B1 (adaptor related protein complex 2 subunit beta 1).
PHENOTYPE: Mice homozygous for a transgenic gene disruption exhibit cleft palate. [provided by MGI curators]
  • synonyms:
  • Ap2b1,
  • expressed sequence AI788979,
  • AI788979,
  • adaptor-related protein complex 2, beta 1 subunit,
  • 1300012O03Rik,
  • RIKEN cDNA 1300012O03 gene,
  • MGI:2144265
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Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

Trail: ProteinCodingGene

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

33 Pathways

Trail: ProteinCodingGene

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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