| Primary Identifier | MGI:87884 | Organism | mouse, laboratory |
| Chromosome | 15 | NCBI Gene Number | 11434 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables peptidase activity. Involved in single fertilization. Acts upstream of or within binding activity of sperm to zona pellucida and penetration of zona pellucida. Located in acrosomal vesicle. Is expressed in testis. Human ortholog(s) of this gene implicated in spermatogenic failure. Orthologous to human ACR (acrosin). PHENOTYPE: Males homozygous for a targeted null mutation produce sperm that shows delayed fertilization in vitro. Sperm from mutant gonial cells are ineffective at fertilization in competition with normal sperm both in vitro and in vivo. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
