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Protein Coding Gene : Adam6b a disintegrin and metallopeptidase domain 6B

Primary Identifier  MGI:2444636 Organism  mouse, laboratory
Chromosome  12 NCBI Gene Number  238405
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable metalloendopeptidase activity. Predicted to be involved in male gonad development and proteolysis. Predicted to be active in external side of plasma membrane and sperm head plasma membrane.
PHENOTYPE: Mice homozygous for null alleles of Adam6a and Adam6b exhibit severely reduced male fertility associated with impaired sperm to sperm interactions and sperm binding to zona pellucida. [provided by MGI curators]
  • synonyms:
  • 4930523C11Rik,
  • Adam6b,
  • RIKEN cDNA 4930523C11 gene,
  • a disintegrin and metallopeptidase domain 6B

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

3 Involved In Mutations

0 Strain

0 Transcripts

1 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For