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Allele : Mepe<tm1Tbrw> matrix extracellular phosphoglycoprotein with ASARM motif (bone); targeted mutation 1, Thomas A Brown

Primary Identifier  MGI:2448895 Allele Type  Targeted
Attribute String  Null/knockout Gene  Mepe
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  The gene was disrupted by replacement of exon 3 with a PGK-neo cassette via homologous recombination, resulting in deletion of amino acids 27-441. Northern blot analysis of tibia RNA from homozygous animals did not detect transcripts. Immunohistochemistry of tibia sections from homozygous mutant mice confirmed the absence of gene product.
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

8 Publication categories

Trail: Allele