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Protein Domain : Zinc finger BED domain-containing protein 2/3

Primary Identifier  IPR043471 Type  Family
Short Name  ZBED2/3
description  Zinc-finger BED domain-containing protein 3 (Zbed3) is a zinc finger protein that binds to axin and activates the Wnt/beta-catenin signalling. Interaction with axin is important for Zbed3 to inhibit beta-catenin phosphorylation, hence inhibiting beta-catenin degradation []. Zbed3 has been associated with insulin resistance and type 2 diabetes mellitus in humans [, ].This entry includes ZBED2 and ZBED3. The function of ZBED2 is not clear.
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1 Child Features

Trail: ProteinDomain

0 Parent Features

4 Protein Domain Regions

Trail: ProteinDomain




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