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Protein Coding Gene : Trpm3 transient receptor potential cation channel, subfamily M, member 3
Primary Identifier  MGI:2443101 Organism  mouse, laboratory
Chromosome  19 NCBI Gene Number  226025
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable calcium channel activity. Predicted to be involved in calcium ion transmembrane transport. Predicted to act upstream of or within monoatomic cation transport. Predicted to be active in plasma membrane. Is expressed in cochlea; liver; nervous system; and retina. Used to study cataract and microphthalmia. Human ortholog(s) of this gene implicated in cataract. Orthologous to human TRPM3 (transient receptor potential cation channel subfamily M member 3).
PHENOTYPE: Homozygous knockout leads to impaired thermal and chemical nociception. Homozygous KO also results in small eyes and lenses, while a specific point mutation additionally leads to cataracts. [provided by MGI curators]
  • synonyms:
  • B930001P07Rik,
  • transient receptor potential cation channel, subfamily M, member 3,
  • MGI:2662432,
  • AU018608,
  • melastatin 2,
  • MLSN2,
  • MGI:2147643,
  • expressed sequence AU018608,
  • RIKEN cDNA B930001P07 gene,
  • RIKEN cDNA 6330504P12 gene,
  • Trpm3,
  • LTRPC3,
  • 6330504P12Rik
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