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Protein Coding Gene : Slc4a10 solute carrier family 4, sodium bicarbonate cotransporter-like, member 10

Primary Identifier  MGI:2150150 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  94229
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables sodium,bicarbonate:chloride antiporter activity and sodium:bicarbonate symporter activity. Involved in regulation of short-term neuronal synaptic plasticity and visual perception. Acts upstream of or within several processes, including brain development; locomotory exploration behavior; and proton transmembrane transport. Located in several cellular components, including basolateral plasma membrane; dendrite; and neuronal cell body. Is expressed in several structures, including gut; nervous system; sensory organ; and testis. Orthologous to human SLC4A10 (solute carrier family 4 member 10).
PHENOTYPE: Mice with homozygous disruption of this gene exhibit reduced brain ventricle volume, reduced neuronal excitability, impaired pH regulation of neurons, and increased threshold to induced seizures. [provided by MGI curators]
  • synonyms:
  • NCBE,
  • Slc4a10,
  • solute carrier family 4, sodium bicarbonate cotransporter-like, member 10

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

4 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For