| Primary Identifier | MGI:105107 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 18442 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable A1 adenosine receptor binding activity; ATP binding activity; and G protein-coupled UTP receptor activity. Acts upstream of or within positive regulation of mucus secretion. Predicted to be located in apical plasma membrane and basolateral plasma membrane. Predicted to be active in glutamatergic synapse and presynaptic active zone membrane. Predicted to colocalize with early endosome. Is expressed in lung. Orthologous to human P2RY2 (purinergic receptor P2Y2). PHENOTYPE: Mice homozygous for a disruption in this gene display reduced nucleotide-stimulated calcium secretion from lung fibroblasts and nasal and tracheal epithelial cells and chloride secretion from trachea and gallbladder. Induction of neuronal differentiationby ATPgammaS is abolished. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
