| Primary Identifier | MGI:1918464 | Organism | mouse, laboratory |
| Chromosome | 16 | NCBI Gene Number | 68606 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable calmodulin-dependent protein phosphatase activity and protein tyrosine/serine/threonine phosphatase activity. Predicted to be involved in several processes, including negative regulation of cell-cell adhesion mediated by cadherin; negative regulation of nitrogen compound metabolic process; and positive regulation of cellular component biogenesis. Predicted to act upstream of or within apoptotic process. Predicted to be located in perinuclear region of cytoplasm. Predicted to be part of protein-containing complex. Predicted to be active in cytosol and nucleus. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and respiratory system. Orthologous to human PPM1F (protein phosphatase, Mg2+/Mn2+ dependent 1F). PHENOTYPE: Mice homozygous for a targeted mutation are not detected at weaning. Mice heterozygous for a targeted mutation display hyperactivity and an increase in pain threshold. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
