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Protein Coding Gene : Mvk mevalonate kinase
Primary Identifier  MGI:107624 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  17855
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Enables mevalonate kinase activity. Predicted to be involved in several processes, including cholesterol biosynthetic process; isopentenyl diphosphate biosynthetic process, mevalonate pathway; and negative regulation of translation. Predicted to act upstream of or within cholesterol metabolic process; phosphorylation; and sterol biosynthetic process. Predicted to be located in peroxisome. Predicted to be active in cytosol. Is expressed in several structures, including alimentary system; brain; genitourinary system; sensory organ; and skeleton. Human ortholog(s) of this gene implicated in lipid metabolism disorder; mevalonic aciduria; and porokeratosis. Orthologous to human MVK (mevalonate kinase).
  • synonyms:
  • RIKEN cDNA 2310010A05 gene,
  • expressed sequence AI256848,
  • MGI:2140825,
  • AI256848,
  • MGD-MRK-36198,
  • mevalonate kinase,
  • AI414037,
  • expressed sequence AI414037,
  • MGI:1917348,
  • MGI:2140856,
  • 2310010A05Rik,
  • Mvk
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Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

Trail: ProteinCodingGene

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

4 Pathways

Trail: ProteinCodingGene

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For





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