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Protein Coding Gene : Cd79b CD79B antigen

Primary Identifier  MGI:96431 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  15985
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables identical protein binding activity and transmembrane signaling receptor activity. Involved in B cell receptor signaling pathway. Acts upstream of or within response to bacterium. Located in external side of plasma membrane. Part of B cell receptor complex. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Human ortholog(s) of this gene implicated in agammaglobulinemia 6 and lymphoma (multiple). Orthologous to human CD79B (CD79b molecule).
PHENOTYPE: Homozygotes for targeted null mutations exhibit arrested development of B cells at the pro-B cell stage due to diminished signaling of the B cell receptor. [provided by MGI curators]
  • synonyms:
  • CD79B antigen,
  • Igb,
  • immunoglobulin-associated beta,
  • MGD-MRK-11225,
  • Cd79b,
  • Igbeta,
  • B29,
  • Ig-beta

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

3 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

5 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For