Primary Identifier | MGI:5316132 | Allele Type | Targeted |
Gene | Lat2 | Transmission | Germline |
Strain of Origin | Not Specified | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Exons 7 through 12 were replaced with the corresponding sequence with nucleotide substitutions that result in the amino acid substitution of phenylalanine for tyrosine at positions 98, 121, 139, 160 and 192. A floxed neo cassette was inserted downstream of exon 6 and removed by cre-mediated recombination. |