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Protein Domain : Destrin

Primary Identifier  IPR029924 Type  Family
Short Name  Dstn
description  Destrin (Dstn) is an actin depolymerising factor that maintains a homeostatic ratio of actin in two forms, filamentous actin (F-actin) and globular actin (G-actin). It severs actin filaments (F-actin) and binds to actin monomers (G-actin). Mutations in Destrin gene lead to abnormalities in the structure and function of the cornea and subsequent blindness in mice [, ].

0 Child Features

1 Parent Features

2 Protein Domain Regions