| First Author | Woodall CJ | Year | 1994 |
| Journal | Gene | Volume | 150 |
| Issue | 2 | Pages | 371-3 |
| PubMed ID | 7821809 | Mgi Jnum | J:23025 |
| Mgi Id | MGI:70657 | Doi | 10.1016/0378-1119(94)90455-3 |
| Citation | Woodall CJ, et al. (1994) Sequence and chromosomal localisation of the gene encoding ovine latent transforming growth factor-beta 1. Gene 150(2):371-3 |
| abstractText | Transforming growth factor-beta 1 (TGF-beta 1) plays important roles in pathologic processes. To further investigate the actions of this cytokine in sheep, the entire 1170-bp ovine TGF-beta 1 pro-protein-encoding sequence has been determined by the cloning and sequencing of specific polymerase-chain-reaction amplification products of TGF-beta 1 cDNA sequences. In addition, these sequences have been used to estimate the length of the TGF-beta 1 mRNA as 1.5-1.7 kb by Northern blot hybridization and determine that the ovine TGF-beta 1 gene occupies a single locus in the sheep genome by chromosomal in situ hybridization. |
