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Protein Coding Gene : Taf4 TATA-box binding protein associated factor 4
Primary Identifier  MGI:2152346 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  228980
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Enables DNA binding activity. Acts upstream of or within DNA-templated transcription and ovarian follicle development. Located in male germ cell nucleus. Is expressed in brain; spinal cord; tail; and thymus. Orthologous to human TAF4 (TATA-box binding protein associated factor 4).
PHENOTYPE: Mice homozygous for deletions of this marker die embryonically sometime around E9.5. Conditional expression of this allele in the epidermis causes skin barrier defects and defects in hair growth. [provided by MGI curators]
  • synonyms:
  • TAF4A RNA polymerase II, TATA box binding protein (TBP)-associated factor,
  • TAFII130,
  • TATA box binding protein (TBP)-associated factor, RNA polymerase II, C1, 130kd,
  • Taf4,
  • Taf4a,
  • MGI:2138960,
  • TAFII135,
  • expressed sequence AI450312,
  • TATA-box binding protein associated factor 4,
  • TATA-box binding protein associated factor 4A,
  • Taf2c1,
  • AI450312
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